منابع مشابه
Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras.
Chimeric mice, generated by aggregating preimplantation embryos, have been instrumental in the study of the development of coat color patterns in mammals. This approach, however, does not allow for direct experimental manipulation of the neural crest cells, which are the precursors of melanoblasts. We have devised a system that allows assessment of the developmental potential and migration of n...
متن کاملNeural crest progenitors and stem cells.
In the vertebrate embryo, multiple cell types originate from a common structure, the neural crest (NC), which forms at the dorsal tips of the neural epithelium. The NC gives rise to migratory cells that colonise a wide range of embryonic tissues and later differentiate into neurones and glial cells of the peripheral nervous system (PNS), pigment cells (melanocytes) in the skin and endocrine cel...
متن کاملThe neural crest stem cells: control of neural crest cell fate and plasticity by endothelin-3.
How the considerable diversity of neural crest (NC)-derived cell types arises in the vertebrate embryo has long been a key question in developmental biology. The pluripotency and plasticity of differentiation of the NC cell population has been fully documented and it is well-established that environmental cues play an important role in patterning the NC derivatives throughout the body. Over the...
متن کاملNeural Crest
Early in the process of development, vertebrate embryos develop a fold on the neural plate [6] where the neural and epidermal ectoderms meet, called the neural crest [7]. The neural crest [7] produces neural crest cells [8] (NCCs), which become multiple different cell types and contribute to tissues and organs as an embryo develops. A few of the organs and tissues include peripheral and enteric...
متن کاملDelivery of Epidermal Neural Crest Stem Cells (EPI-NCSC) to hippocamp in Alzheimer\'s Disease Rat Model
Background: Alzheimer’s disease (AD) is characterized by progressive neuronal loss in hippocamp. Epidermal neural crest stem cells (EPI-NCSC) can differentiate into neurons, astrocytes and oligodendrocytes. The purpose of this study was to evaluate the effects of transplanting EPI-NCSC into AD rat model. Methods: Two weeks after induction of AD by injection of Amyloid-β 1-40 into CA1 area of ra...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1978
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.19.644